Gastrointestinal Stromal Tumors (GIST) Diagnosis, Treatment, and Mnemonics for Clinicians Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal (GI) tract, originating from the interstitial cells of Cajal, which regulate peristalsis. While GISTs can occur anywhere along the GI tract, the stomach (60%) and small intestine (30%) are the most frequent sites.Read More
